The organic anion transporter oat family

Author: kioy

August undefined, 2024

WebbFör 1 dag sedan · Organic anion transporters 1 and 3 (OAT1/3) occupy a key role in mediating renal elimination. Kynurenic acid (KYNA) was previously discovered as an … Webbic anion transporter families, e.g. the organic anion trans-porting polypeptide (oatp) family or the Mrp (multidrug resistance-associated protein) family. On the other hand, the …

In Vitro and In Vivo Evidence of the Importance of Organic Anion ...

WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be … Webb11 apr. 2024 · Glycine synthase (AMT), a solute organic anion transporter family member (OAT), and fatty acyl-coA reductase (FAR) are predicted to be regulated by multiple … roman stocks in prison

The organic anion transporter (OAT) family: a systems biology ...

Webb31 dec. 2014 · Open Access The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received … Webb1 jan. 2015 · Abstract The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal … Webb10 juli 2024 · Since, in the Oat3KO, the basolateral transport of organic anions by PT cells is dependent upon the remaining OAT (i.e., OAT1), treatment with probenecid should … roman stephen king 3 buchstaben

Organo anion transporter family - Wikipedia

Endogenous Biomarker of OAT Inhibition - dmd.aspetjournals.org

Webb1 aug. 2001 · Abstract The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, … Webbsolute carrier family 21 (organic anion transporter), member 11, OATPRP3, FLJ40478, OATP3A1, solute carrier organic anion transporter family member 3A1, PGE1 … roman stoic philosopherWebbThe organic anion transporters ( OAT s), part of the SLC22 superfamily of transporters, are expressed throughout the body. However, the most clinically relevant members of this … roman stitch baby blanket

"Webb多選択性有機アニオントランスポーターファミリー (OAT family)の同定と薬物輸送における役割の解析. 記事の概要. 抄録. 引用文献 (50) 著者関連情報. 共有する. 抄録. 薬物トラ … " - The organic anion transporter oat family

The organic anion transporter oat family

Organic anion transporters and PI3K–AKT–mTOR pathway …

The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o… WebbBxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3. Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously …

Did you know?

WebbThe editors have built ATP-Dependent Organic Anion Transporters—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ … Webb23 juni 2000 · The OAT family represents mainly the renal secretory and reabsorptive pathway for organic anions and is also involved in the distribution of organic anion in the …

WebbSeveral families of multispecific organic anion and cation transporters, including OAT family transporters, have recently been identified by molecular cloning. The OAT family … WebbThus, OATs are members of a much larger group of transporters—the SLC22 (solute carrier 22) family—that includes organic cation, carnitine and urate transporters. …

WebbThe members of the organic anion transporter (OAT) family are mainly expressed in kidney, liver, placenta, intestine, and brain. These transporters play important roles in the … WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention …

Webb1 juni 2000 · Organic anion transporter (OAT) is an heterogenous family of negatively charged proteins, mainly located in kidneys and the liver, but OAT1/OAT3 are also found …

WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention because of … roman stone fortifications pdfWebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … roman story ks2WebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … roman storage benchWebbMany UTs and drugs administered to CKD patients are organic anions, which are physiologically eliminated by the organic anion transporter (OAT) system [6,7]. OATs … roman story ideasWebbOrganic anion transporters (OATs) are shown in red, the organic cation/carnitine transporter (OCTN/CT) family is shown in blue, and organic cation transporters (OCTs) … roman story bookWebb1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … roman stormWebb39 rader · 1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 ... roman stone 48 in. rubber garden edging earth