Phospho-p53 ser15
WebPhospho-p53 (Ser15) Antibody (PA5-78204) in WB. Western Blot using Phospho-p53 (Ser15) Polyclonal Antibody ( Product # PA5-78204 ). Untreated (–) and treated (+) 293T … WebApr 29, 2004 · Indeed, doxorubicin-induced p53 phosphorylation on Ser15 residue in both MCF7 and MCF55a cells (Figures 3a, b and 5b), and this p53Ser15 phosphorylation was not affected by suppression of ERK2 or ...
Phospho-p53 ser15
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WebThe intense phosphorylation of p53-Ser15, combined with activation of ATM and Chk2 (involving centrioles) as well as phosphorylation of H2AX seen in the untreated mitotic …
WebThe NeuroMab™ anti-Phospho-p53 (Ser15) antibody (Rodent Specific) recognizes endogenous levels of p53 protein only when phosphorylated at Ser15. Expression Host … WebJun 7, 2014 · Serine 15 is the primary target of the DNA damage response on the p53 protein and is phosphorylated by both the ATM and ATR protein kinases (discussed in …
WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in … WebWestern blot analysis of a p53 fusion protein, untreated or phosphorylated by DNA-PK, using Phospho-p53 (Ser15) Antibody (upper) and p53 Antibody #9282 (lower). Show More Western blot analysis of extracts from COS cells treated with UV or MMS for the indicated times, using Phospho-p53 (Ser20) Antibody (upper) or p53 Antibody #9282 (lower).
WebDec 1, 1999 · Mutation of these sites decreased p53-mediated and UV-induced apoptosis, and the reduction correlated with total abrogation of UV-induced phosphorylation on Ser37 and a significant decrease in Ser15 phosphorylation in mutant p53 containing alanine at Ser33 and Ser46.
WebPhospho-p53 (Ser15) Translocation Assay Kit (Cell-Based) (ab284565) (K966) provides a simple and complete assay in a ready to use format to visualize the nuclear translocation of activated p53 in mammalian cells. … notice of current real property tax leviesWebPhosphorylated by NUAK1 at Ser-15 and Ser-392; was initially thought to be mediated by STK11/LKB1 but it was later shown that it is indirect and that STK11/LKB1-dependent phosphorylation is probably mediated by downstream NUAK1. It is unclear whether AMP directly mediates phosphorylation at Ser-15. notice of current rent balance documentWebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent. notice of data breach letter scamWeb67826-1-Ig targets Phospho-P53 (Ser15) in WB, FC, ELISA applications and shows reactivity with Human samples. Background Information TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. how to setup clock on desktopWeb80195-1-RR targets Phospho-P53 (Ser15) in WB, FC, ELISA applications and shows reactivity with Human samples. Background Information P53 is a 53 kDa protein that is activated in response to alteration of normal cell homeostasis, including DNA damage, nutrient starvation, heat shock, virus infection, pH change, hypoxia, and oncogene … notice of death dhcsWebA synthetic phospho-peptide corresponding to residues surrounding Ser15 of human phospho p53. Formulation: 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA: Isotype: Rabbit IgGk: Preparation: Protein A+G: Recommended Usage: 1µg/mL – 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. notice of death bir sampleWebB, The relative protein intensities of p53, phospho-p53 (Ser15), phospho-p53 (Thr55), p21, and survivin as compared with the intensity of α-tubulin. The intensity of each band was quantified using Quantity One software. Data are means ± SD, n = 3. The experiments were conducted in triplicate. how to setup cleats cycling biking shimano