Web1 de nov. de 2024 · On powerful GWAS in admixed populations. Hou K, Bhattacharya A, Mester R,Burch KS,Pasaniuc B. Eur J Hum Genet. 2024 Dec 23. doi: 10.1038/s41431-021-00996 ... Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. Pasaniuc B, Zaitlen N, … WebIntroduction. Genome-wide association studies (GWAS) have allowed for significant progress in the field of human complex traits. However, groups with multiple ancestral …
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Web12 de mar. de 2015 · The methodological steps surrounding genetic data generation, quality control, study design and analytical procedures needed to run GWAS in the multiethnic and highly admixed Generation R Study, a large prospective birth cohort in Rotterdam, the Netherlands are described. Genome-wide association studies (GWAS) have been … WebOn powerful GWAS in admixed populations Kangcheng Hou, Arjun Bhattacharya, Rachel Mester, Kathryn S. Burch, Bogdan Pasaniuc Nature Genetics, 2024 2024. Accurate … phonon localization
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Webtransferability of GWAS under directional polygenic selection or varying divergence. We focus on a two-way admixed population and show that GWAS in admixed populations can be enriched for power in discovery by up to 2-fold compared to the ancestral populations under similar sample size. Moreover, higher accuracy of cross-population Web1 de dez. de 2024 · Request PDF On Dec 1, 2024, Elizabeth G. Atkinson and others published Reply to: On powerful GWAS in admixed populations Find, read and cite … Web9 de mar. de 2024 · 32 show that GWAS in admixed populations can be enriched for power in discovery by up to 2-fold 33 compared to the ancestral populations under similar sample size. ... This would theoretically result in greater power of discovery in GWAS, as the analysis 91 is most powerful for variants with higher minor allele frequency. phonon negative gravity